Results: 1019

Stability indicating Rp-UPLC method development and validation for the simultaneous estimation of fosnetupitant and palonosetron in bulk and injection dosage form

Abstract A stability indicating UPLC method has been developed and validated for the simultaneous determination of fosnetupitant and palonosetron in bulk and in injection dosage form. This combination is used for the prevention of acute and delayed nausea and vomiting associated with initial and repeated...

Solubility enhancementofcefixime trihydrate by solid dispersions using hydrotropic solubilization technique and their characterization

Abstract The aqueous solubility of cefixime trihydrate (a water insoluble drug) using different hydrotropic agents was determined and solid dispersions of cefixime trihydrate were prepared by hydrotropic solubilization technique. The drugs content were determined. The aqueous solubility of v was increase...

Validação de vídeo instrucional sobre banho de ofurô em recém-nascido pré-termo para enfermeiros

Resumo Objetivo Produzir um vídeo instrucional para enfermeiros sobre o banho de ofurô em recém-nascidos pré-termo e validar seu conteúdo. Método Estudo metodológico de desenvolvimento tecnológico com ênfase na validação de conteúdo, conduzido em três etapas: revisão exploratória da lite...

Psicanálise, grupo e teoria da técnica: conselhos ao jovem coordenador de grupos

Psicol. USP; 33 (), 2022
Resumo Atualmente, na universidade, os estudos e pesquisas sobre psicanálise e grupos vêm aumentando. Contudo, muitos trabalhos sobre intervenção em grupos não descrevem como se realiza a análise grupal. Dessa forma, o objetivo deste artigo é sistematizar uma proposta de análise da cadeia associa...

Sustained release matrix tablet of 100 mg losartan potassium: Formulation development and in vitro characterization

Abstract Sustained release matrix tablets of 100 mg losartan potassium HCl were fabricated with two release retarding polymers namely HPMC K100 M and affinisol by direct compression method. Nine trial formulations were prepared by varying content of these polymers, each from 50 mg to 100 mg; keeping the...

Effect of carrier materials on the properties of the andrographolide solid dispersion

Abstract In the work the andrographolide (AG)-solid dispersions (SDs) were prepared by the spray-drying method, using polyethylene glycol 8000 (PEG8000), Poloxamer188, polyvinylpyrrolidone K30 (PVPK30), Soluplus® as carrier materials. The effect of different polymers as carrier materials on the properti...

Equivalência da escala de luto perinatal para escala de luto parental após a perda de um filho

Ciênc. cuid. saúde; 21 (), 2022
RESUMO Introdução: a manifestação mais comum do luto complicado é diante da morte de um filho. Neste contexto, observa-se a emergência da utilização de escalas direcionadas para pais na identificação do luto parenteral. Objetivo: realizar equivalência da Escala de Luto Perinatal para Escala ...

Características del SARS-CoV-2, COVID-19 y su diagnóstico en el laboratorio

Med. lab; 26 (3), 2022
La enfermedad COVID‑19 es causada por el virus SARS-CoV-2, descrito por primera vez en diciembre del 2019 en Wuhan, China, y declarada en marzo del 2020 como una pandemia mundial. Actualmente existen diversos métodos diagnósticos para COVID-19, siendo el estándar de oro la detección del material ge...

Pain and physical activity for one individual: a comparison of models

Aims: there is increasing awareness that for effective patient care we need more than only randomized controlled trials with groups of participants and that carefully collected single case (N = 1) data have several important advantages over traditional group-level studies. With the advance of technology,...

Gender Dysphoria Publication Trends: A Bibliometric Analysis between 1900 and 2018

Objective Research on gender dysphoria (GD) has been growing over the last decades with increasing interest in understanding and characterizing the causal relationships between psychological, genetics, hormonal, and sociocultural factors. Changes and acceptance of this condition as non-pathologic have ...