Abstract In this study we evaluated the long-term spatial memory in humans. A quasiexperimental design was used in which three groups of undergraduate students were trained in a virtual water maze to locate a hidden platform whose location was indicated by a set of cues. A pre-test without platform was p...
ABSTRACT In this study, the effect of thymoquinone (TQ) on propylthiouracil (PTU)-induced memory impairment was investigated in juvenile rats. The rats were grouped into control, Hypo, Hypo-TQ5 and Hypo-TQ10. Propylthiouracil increased latency time in the Morris water maze test and decreased delay in ent...
Antioxidantes/farmacología,
Antitiroideos,
Reacción de Prevención/efectos de los fármacos,
Benzoquinonas/farmacología,
Lesiones Encefálicas/metabolismo,
Catalasa/análisis,
Modelos Animales de Enfermedad,
Hipocampo/efectos de los fármacos,
Hipotiroidismo/inducido químicamente,
Hipotiroidismo/complicaciones,
Discapacidades para el Aprendizaje/inducido químicamente,
Discapacidades para el Aprendizaje/tratamiento farmacológico,
Malondialdehído/análisis,
Aprendizaje por Laberinto/efectos de los fármacos,
Trastornos de la Memoria/inducido químicamente,
Trastornos de la Memoria/tratamiento farmacológico,
Óxido Nítrico/análisis,
Estrés Oxidativo/efectos de los fármacos,
Propiltiouracilo,
Ratas Wistar,
Superóxido Dismutasa/análisis
Attention and emotion have a positive impact on memory formation, which is related to the activation of the noradrenergic system in the brain. The hippocampus and amygdala are fundamental structures in memory acquisition, which is modulated by noradrenaline through the noradrenergic receptors. Pharmacolo...
Lin, Ruhui;
Li, Long;
Zhang, Yingzheng;
Huang, Sheng;
Chen, Shangjie;
Shi, Jiao;
Zhuo, Peiyuan;
Jin, Hao;
Li, Zuanfang;
Liu, Weilin;
Wang, Zhifu;
Chen, Lidian;
Tao, Jing.
OBJECTIVE: To explore the precise mechanism of electroacupuncture (EA) to delay cognitive impairment in Alzheimer disease. Methods N -Acetylaspartate (NAA), glutamate (Glu) and myoinositol (mI) metabolism were measured by magnetic resonance spectroscopy, learning and memory of APP/PS1 mouse was evaluate...
Ácido Aspártico/análogos & derivados,
Electroacupuntura/métodos,
Ácido Glutámico/metabolismo,
Hipocampo/química,
Aprendizaje/fisiología,
Memoria/fisiología,
Ácido Aspártico/metabolismo,
Hipocampo/diagnóstico por imagen,
Inositol/análisis,
Glicoproteínas de Membrana/análisis,
Proteínas Tirosina Quinasas/análisis,
Western Blotting,
Factor Neurotrófico Derivado del Encéfalo,
Prueba de Esfuerzo,
Imagen por Resonancia Magnética,
Espectroscopía de Resonancia Magnética,
Aprendizaje por Laberinto,
Ratones Transgénicos,
Modelos Animales,
Distribución Aleatoria
Abstract Introduction: Children and adolescents living in shelters may present with impaired motor development, cognitive function, as well as speech and understanding; psychological alterations; and hyperactivity. All of these factors may be detrimental to motor learning. Objective: To investigate m...
Abstract Purpose: To evaluate the effects of HBO (Hyperbaric oxygen) and NGF (Nerve growth factor) on the long-term neural behavior of neonatal rats with HIBD (Neonatal hypoxic ischemic brain damage). Methods: The HIBD model was produced by ligating the right common carotid artery of 7 days old SD (Spr...
Coimbra, Norberto C;
Paschoalin-Maurin, Tatiana;
Bassi, Gabriel S;
Kanashiro, Alexandre;
Biagioni, Audrey F;
Felippotti, Tatiana T;
Elias-Filho, Daoud H;
Mendes-Gomes, Joyce;
Cysne-Coimbra, Jade P;
Almada, Rafael C;
Lobão-Soares, Bruno.
Objective: To compare prey and snake paradigms performed in complex environments to the elevated plus-maze (EPM) and T-maze (ETM) tests for the study of panic attack- and anticipatory anxiety-like behaviors in rodents. Methods: PubMed was reviewed in search of articles focusing on the plus maze test, EP...
We aimed to investigate the potential role and mechanism of microRNA-30c (miR-30c) in the pathological development of chronic hepatitis B (CHB). The serum levels of miR-30c in hepatitis B virus (HBV) carrier Xinjiang Uygur patients with inactive, low-replicative, high-replicative and HBe antigen-positive...
Carcinoma Hepatocelular/genética,
Carcinoma Hepatocelular/patología,
Proliferación Celular/genética,
China,
Progresión de la Enfermedad,
Regulación hacia Abajo,
Regulación Viral de la Expresión Génica,
Virus de la Hepatitis B/genética,
Hepatitis B Crónica/sangre,
Hepatitis B Crónica/etnología,
Neoplasias Hepáticas/genética,
Neoplasias Hepáticas/patología,
Aprendizaje por Laberinto,
MicroARNs/sangre
The Quechua term ayahuasca refers to a beverage obtained from decoctions of the liana Banisteriopsis caapi with leaves of Psychotria viridis. The ritualistic use of ayahuasca is becoming a global phenomenon, with some individuals using this beverage throughout life, including in old age. Cognitive impair...
Envejecimiento/fisiología,
Ansiedad/inducido químicamente,
Banisteriopsis/química,
Bebidas,
Locomoción/efectos de los fármacos,
Aprendizaje por Laberinto/efectos de los fármacos,
Memoria/efectos de los fármacos,
Ratones Endogámicos C57BL,
Modelos Animales,
Psychotria/química,
Factores de Tiempo
Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups. However, little is known of the effects of ayahuasca during ontogenic development, particularly with regard to the functional characteris...
