Results: 354

Current use and acceptability of novel diagnostic tests for active tuberculosis: a worldwide survey

J. bras. pneumol; 43 (5), 2017
ABSTRACT Objective: To determine the current use and potential acceptance (by tuberculosis experts worldwide) of novel rapid tests for the diagnosis of tuberculosis that are in line with World Health Organization target product profiles. Methods: A multilingual survey was disseminated online between Ju...

A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge

Abstract The prognosis of tuberculous meningitis, a rare form of extrapulmonary tuberculosis, depends on the stage of treatment initiation. We report a fatal case of tuberculous meningitis. The patient had received successive tumor necrosis factor (TNF) antagonists and abatacept to treat juvenile idiopat...

Búsqueda de tuberculosis latente en poblaciones especiales: Diabetes

Acta méd. colomb; 42 (3), 2017
La tuberculosis latente (TBL) se define como la presencia de una respuesta específica inmune al Mycobacterium tuberculosis en ausencia de enfermedad clínica y radiológica (1), esta condición, al presentarse en personas sin signos o síntomas de tuberculosis no es reportada generalmente y los datos ep...

IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage

Braz. j. infect. dis; 21 (4), 2017
Abstract Mycobacterium tuberculosis (MTB) adopts a special survival strategy to overcome the killing mechanism(s) of host immune system. Amongst the many known factors, small heat shock protein 16.3 (sHSP16.3) of MTB encoded by gene hspX has been reported to be critical for the survival of MTB. In the pr...

Evaluation of the commercial kit SIRE nitratase for detecting resistant mycobacterium tuberculosis in Brazil

Abstract INTRODUCTION: This study aimed to evaluate a new commercial kit, Kit SIRE Nitratase-PlastLabor, for testing the drug susceptibility of clinical Mycobacterium tuberculosis isolates. METHODS: The accuracy of the Kit SIRE Nitratase was evaluated by examining the susceptibility (streptomycin, ison...

Evaluación de la técnica Xpert® MTB/RIF para la detección de Mycobacterium tuberculosis complex en muestras extra-pulmonares

Rev. chil. infectol; 34 (4), 2017
Resumen La tuberculosis (TBC) extra-pulmonar alcanza al 26,2% de los casos totales de TBC en Chile. El cultivo es el método estándar de oro, pero es lento. La técnica Xpert® MTB/RIF permite detectar Mycobacterium tuberculosis complex (MTBc) por RPC en tiempo real en menos de 3 h, sin embargo, ha sido...

Tuberculose em felinos domésticos (Felis catus) no sul do Rio Grande do Sul

Pesqui. vet. bras; 37 (7), 2017
Descrevem-se os aspectos clínico patológicos de quatro casos de tuberculose em felinos domésticos no Sul do Rio Grande do sul. Foi realizado um estudo retrospectivo dos casos diagnosticados como tuberculose em gatos necropsiados no Laboratório Regional de Diagnóstico da Universidade Federal de Pelot...

Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus

Mem. Inst. Oswaldo Cruz; 112 (6), 2017
BACKGROUND To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range of drug resistance related genetic markers in the Mycobacterium tuberculosis genome are urgently needed. OBJECTIVE To evaluate the performance...

A systematic review of East African-Indian family of Mycobacterium tuberculosis in Brazil

Braz. j. infect. dis; 21 (3), 2017
ABSTRACT Introduction: The Mycobacterium tuberculosis East African-Indian (EAI) spoligotyping family (belonging to lineage 1, Indo-Oceanic, defined by the region of deletion RD239) is distributed worldwide, but is more prevalent in Southeast Asia, India, and East Africa. Studies in Latin America have ra...