Abstract INTRODUCTION: In this study, we used phenotypic methods to screen carbapenem-resistant Enterobacteriaceae (CREs) and evaluated their antimicrobial sensitivity profile. METHODS: One hundred and seventy-eight CREs were isolated at a university hospital in south Brazil in a one-year period. Samp...
Abstract The purpose of this study was to identify the risk factors that predispose patients who are hospitalized with pressure ulcers (PUs) colonized by Gram-negative bacilli (GNB) to develop bacteremia. In addition, we also detected main phenotypes of resistance in infected and uninfected PUs. A prospe...
Objetivo: A identificação dos fenótipos da asma permite uma melhor compreensão e abordagem desta doença heterogênea. Muitos estudos têm demonstrado associação entre os antígenos leucocitários humanos (HLA) e asma em diversas populações, porém os resultados são inconclusivos e raramente con...
Antígenos HLA-DP,
Asma,
Antígenos HLA-B,
Antígenos HLA-C,
Fenotipo,
Genotipo,
Donantes de Tejidos,
Antígenos HLA-DQ,
Grupos Control,
Inmunoglobulina E,
Índice de Severidad de la Enfermedad
Background: Assessments of genetic diversity are essential for germplasm characterization and exploitation. Molecular markers are valuable tools for exploring genetic variation and identifying germplasm. They play key roles in a Xanthoceras sorbifolia breeding program. Results: We analyzed the genetic di...
Sapindaceae/genética,
Variación Genética,
Fenotipo,
Repeticiones de Microsatélite,
China,
Marcadores Genéticos,
Semillas/genética,
ADN de Plantas,
Aceites de Plantas,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético
ABSTRACT Hypertrophic cardiomyopathy is known as Leopard syndrome, which is a mnemonic rule for multiple lentigines (L), electrocardiographic conduction abnormalities (E), ocular hypertelorism (O), pulmonary stenosis (P), abnormalities of genitalia (A), retardation of growth (R), and deafness (D). We rep...
Abstract: Approximately 10% of individuals do not respond to hepatitis B virus (HBV) vaccination, i.e. non-responders (NRs). We aimed to investigate the association of interleukin (IL)-4 and IL-12B gene polymorphisms with responsiveness to the HBV vaccine in Korean infants. Among 300 healthy infants (9-1...
Vacunas contra Hepatitis B/administración & dosificación,
Hepatitis B/prevención & control,
Subunidad p40 de la Interleucina-12/genética,
Interleucina-4/genética,
Polimorfismo de Nucleótido Simple,
Biomarcadores/sangre,
Frecuencia de los Genes,
Anticuerpos Antihepatitis/sangre,
Hepatitis B/genética,
Hepatitis B/inmunología,
Antígenos de Superficie de la Hepatitis B/sangre,
Esquemas de Inmunización,
Fenotipo,
Farmacogenética,
Factores de Tiempo,
Resultado del Tratamiento,
Vacunación,
República de Corea
ABSTRACT The definition of neuromyelitis optica (NMO) is still evolving. In 2015, the International Panel for NMO Diagnosis was convened to develop revised diagnostic criteria. There have been few studies on NMO in the Brazilian population. Objective To describe the characteristics of 34 Brazilian NMO ...
Abstract The mechanisms involved in the uncommon resistance phenotype, carbapenem resistance and broad-spectrum cephalosporin susceptibility, were investigated in 25 Pseudomonas aeruginosa clinical isolates that exhibited this phenotype, which were recovered from three different hospitals located in São...
Antibacterianos/farmacología,
Proteínas de la Membrana Bacteriana Externa,
Proteínas Bacterianas/metabolismo,
Brasil,
Carbapenémicos/farmacología,
Cefalosporinas/farmacología,
ADN Bacteriano,
Electroforesis en Gel de Campo Pulsado,
Pruebas de Sensibilidad Microbiana,
Fenotipo,
Porinas/metabolismo,
Pseudomonas aeruginosa/efectos de los fármacos,
Pseudomonas aeruginosa/enzimología,
Pseudomonas aeruginosa/genética,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Análisis de Secuencia de ADN,
Espectrofotometría Ultravioleta,
Resistencia betalactámica/genética,
beta-Lactamasas/metabolismo
ABSTRACT CONTEXT AND OBJECTIVE: The association of serum triglycerides plus waist circumference seems to be a good marker of cardiovascular risk and has been named the “hypertriglyceridemic waist” phenotype. The aim of our study was to investigate the association between the hypertriglyceri...
Abstract Compound heterozygosity has been described in inherited arrhythmias, and usually associated with a more severe phenotype. Reports of this occurrence in Brugada syndrome patients are still rare. We report a study of genotype-phenotype correlation after the identification of new variants by geneti...
Aleteo Atrial/genética,
Aleteo Atrial/fisiopatología,
Síndrome de Brugada/genética,
Síndrome de Brugada/fisiopatología,
Electrocardiografía,
Predisposición Genética a la Enfermedad,
Heterocigoto,
Mutación,
Canal de Sodio Activado por Voltaje NAV1.5/genética,
Linaje,
Fenotipo,
Índice de Severidad de la Enfermedad
