Results: 148

Caracterização de polimorfismos nos genes OPG, RANK e RANKL em uma população brasileira

Introdução: o sistema RANKL (receptor-ativador do fator nuclear-ligante κB)/RANK (receptor ativador do NF-kB)/OPG (osteoprotegrina) Introdução: o sistema OPG (osteoprotegrina)/RANK (receptor ativador do NF-kB)/RANKL (receptor-ativador do fator nuclear-ligante κB) regula os processos fisiológicos e...

Screening of Variants in the Transcript Profile of Eutopic Endometrium from Infertile Women with Endometriosis during the Implantation Window

Abstract Objective Abnormalities in the eutopic endometrium of women with endometriosis may be related to disease-associated infertility. Although previous RNA-sequencing analysis did not show differential expression in endometrial transcripts of endometriosis patients, other molecular alterations coul...

Autotrasplante Dental Utilizando Simulación Virtual y un Prototipo de Modelo de Impresión 3D

La técnica de autotrasplante dental se ideó como opción terapéutica ante la pérdida o ausencia de dientes por traumatismos, caries, agenesias, exfoliación temprana, iatrogenias, u otros factores. Consiste en extraer un diente desde su posición original para implantarlo en un solo acto quirúrgico ...

Simulação virtual por meio de um serious game sobre segurança do paciente: um estudo experimenta

Introdução: A segurança do paciente tem ganhado destaque e amplo debate no processo de formação dos estudantes da área da saúde, assim como na enfermagem. O uso de tecnologia digital educacional, como o serious game, pode ser utilizado como estratégia em atividades de simulação virtual que, por...

Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs

he resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal products. In this context, toxinology is a multidisciplinary approach on the development of new dru...

In silico and in vitro evaluation of primers for molecular differentiation of Leishmania species

Abstract Leishmaniasis is a zoonotic disease caused by over 20 species of protozoan parasites of the genus Leishmania. Infection is commonly spread by sandflies and produces a wide spectrum of clinical signs and symptoms. Therefore, from an epidemiological and therapeutic standpoint, it is important to d...

Development and validation of a simulator for teaching minimally invasive thoracic surgery in Brazil

Acta cir. bras; 36 (5), 2021
ABSTRACT Purpose To develop and validate a chest cavity simulator for teaching video-assited thoracic surgery (VATS). Methods The first phase of the study consisted of developing a chest cavity simulator. A quasi-experimental study was performed in the second phase, and 25 surgeons and residents partic...

Training in robotic surgery: initial experience using the Brazilian College of Surgeons model

Rev. Col. Bras. Cir; 48 (), 2021
ABSTRACT Objective: to present the initial experience of the first tier of surgeons trained in the new model of robotic surgery training proposed by the CBC. Methods: we retrospectively collected data and information on training with the Da Vinci SI robotic system. The variables analyzed were, in the...

In silico, in vitro, and ex vivo studies of the toxicological and pharmacological properties of the flavonoid 5,7-dihydroxy-3,8,4'-trimethoxy

Braz. j. med. biol. res; 54 (10), 2021
Phytochemical studies of the species Pavonia glazioviana were performed. Quercetin, kaempferol, acacetin, and trimethoxylated flavonoid compounds (which present biological activity) were isolated. We aimed to evaluate the in silico, in vitro, and ex vivo toxicity of flavonoid 5,7-dihydroxy-3,8,4'-trimeth...

Computational classification of animals for a highway detection system

Vehicle-animal collisions represent a serious problem in roadway infrastructure. To avoid these roadway collisions, different mitigation systems have been applied in various regions of the world. In this article, a system for detecting animals on highways is presented using computer vision ...