Results: 5032

Monitoring the emergence of HBV resistance mutations by HBV-RNA pyrosequencing

Braz. j. infect. dis; 20 (2), 2016

Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China

Braz. j. infect. dis; 20 (2), 2016
Abstract Objective There are a lot of disagreements in the studies on hepatitis B virus (HBV) DNA polymerase mutation rate associated with nucleos(t)ide analogues (NAs) in treatment-naive chronic hepatitis B (CHB) patients. This is the first study aimed to investigate the prevalence of spontaneous HBV r...

Carbapenem-resistant Klebsiella pneumoniae colonization in pediatric and neonatal intensive care units: risk factors for progression to infection

Braz. j. infect. dis; 20 (2), 2016
Abstract Background Little is known about factors associated with carbapenem-resistant Klebsiella pneumoniae infections in pediatric patients, who are initally colonized with carbapenem-resistant Klebsiella pneumoniae. Materials and methods A retrospective case–control study was conducted involvi...

Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration values of itraconazole against Histoplasma capsulatum strains in vitro

Braz. j. infect. dis; 20 (2), 2016
Abstract Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavir and ritonavir, a...

Detection of multidrug-resistant Mycobacterium tuberculosis strains isolated in Brazil using a multimarker genetic assay for katG and rpoB genes

Braz. j. infect. dis; 20 (2), 2016
Abstract Multidrug-resistant tuberculosis (MDRTB) is a serious world health problem that limits public actions to control tuberculosis, because the most used anti-tuberculosis first-line drugs fail to stop mycobacterium spread. Consequently, a quick detection through molecular diagnosis is essential to r...

Photodynamic action of protoporphyrin IX derivatives on Trichophyton rubrum

An. bras. dermatol; 91 (2), 2016
Abstract: BACKGROUND: Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacke...

Influence of prolonged use of desensitizing dentifrices on dentin bond strength of self-etching adhesive system

Dentin hypersensitivity is a relatively common clinical condition, which affects a large part of the world's population. The objective of this study was to evaluate the influence of previous and prolonged treatment with desensitizing dentifrices (DD) on bond strength to dentin, promoted by a self-etching...

Susceptibilidad antimicrobiana de microorganismos anaerobios aislados de infecciones endodónticas primarias a amoxicilina y metronidazol y su asociación con los parámetros clínicos: serie de casos

El objetivo de este estudio es describir la composición de la microbiota anaerobia estricta/aerotolerante en infecciones endodónticas primarias, su susceptibilidad antimicrobiana, y la asociación con los parámetros clínicos. Se tomaron muestras de siete pacientes con necrosis pulpar sintomática o a...

Corneal collagen cross-linking for progressive keratoconus in patients aged 9 to 14

Rev. bras. oftalmol; 75 (2), 2016
RESUMO Objetivo: Determinar a segurança e eficácia do cross-linking corneano (CXL) em pacientes de 9 a 14 anos de idade com ceratocone progressivo. Métodos: Dezesseis olhos de onze pacientes (8 homens e 3 mulheres) com ceratocone progressivo foram submetidos ao CXL, de acordo com o protocolo padrão...