Results: 41

Design and optimization of self-microemulsifying drug delivery system (SMEDDS) of felodipine for chronotherapeutic application

Braz. j. pharm. sci; 50 (1), 2014
The objective of this research work was to design, develop and optimize the self micro-emulsifying drug delivery system (SMEDDS) of Felodipine (FL) filled in hard gelatine capsule coated with polymer in order to achieve rapid drug release after a desired time lag in the management of hypertension. Microe...

Characterization and stability studies of emulsion systems containing pumice

Braz. j. pharm. sci; 50 (2), 2014
Emulsions are the most common form of skin care products. However, these systems may exhibit some instability. Therefore, when developing emulsions for topical application it is interesting to verify whether they have suitable physical and mechanical characteristics and further assess their stability. Th...

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Braz. j. pharm. sci; 50 (3), 2014
Euterpe oleracea Mart. is a palm tree popularly known as açai, which is primarily found in northern Brazil. The açai's fruits contain anthocyanins, a class of polyphenols to which antioxidant properties have been attributed. The aim of this work was to develop O/W sunscreens emulsions containing açai ...

Determination of the critical hydrophile-lipophile balance of licuri oil from Syagrus coronata: application for topical emulsions and evaluation of its hydrating function

Braz. j. pharm. sci; 49 (1), 2013
The aims of this study were to determine the critical hydrophile-lipophile balance (HLB) of licuri oil, and to perform a clinical assay to evaluate its hydrating effects. For the determination of the HLB, serial emulsions were prepared with the oil. Regarding the clinical study, 13 human subjects were re...

Study of thermal behavior of phytic acid

Braz. j. pharm. sci; 49 (2), 2013
Phytic acid is a natural compound widely used as depigmenting agent in galenic cosmetic emulsions. However, we have observed experimentally that phytic acid, when heated to 150 ºC for around one hour, shows evidence of thermal decomposition. Few studies investigating this substance alone with regard to ...

Fabrication, physicochemical characterization and preliminary efficacy evaluation of a W/O/W multiple emulsion loaded with 5% green tea extract

Braz. j. pharm. sci; 49 (2), 2013
Complex multiple emulsions have an excellent ability to fill large volumes of functional cosmetic agents. This study was aimed to encapsulate large volume of green tea in classical multiple emulsion and to compare its stability with a multiple emulsion without green tea extract. Multiple emulsions were d...

Development, characterization and antioxidant activity of polysorbate based O/W emulsion containing polyphenols derived from Hippophae rhamnoides and Cassia fistula

Braz. j. pharm. sci; 49 (4), 2013
The objective of this study was to develop a pharmaceutical O/W emulsion containing plant-derived polyphenol extracts and evaluate its stability and antioxidant activity. O/W emulsions were prepared using ionic surfactant polysorbate 80 (Tween 80®). The odorwas adjusted with few drops of blue sea fragra...

Modelagem matemática na avaliação do sinergismo da atividade antioxidante de compostos naturais aplicados em emulsões alimentícias

O crescimento do mercado de alimentos funcionais e orgânicos, assim como a maior conscientização do consumidor em relação aos efeitos tóxicos e mutagênicos de alguns aditivos artificiais, tem impulsionado a indústria a substituir compostos artificiais por naturais. Emulsões alimentícias, como s...

Principios básicos de la higiene de la piel y de los productos usados para la limpieza cutánea
Basic principles of skin hygiene and products used for the cutaneous cleaning

Rev. chil. dermatol; 13 (4), 1997
La higiene de la piel tiene como objetivo eliminar la suciedad de su superficie, compuesta por residuos fisiológicos y ambientales. Permite, además, prevenir la infección y suprimir olores desagradables. Para estos fines se requieren tensoactivos, substancias anfifílicas capaces de remover los elemen...

Propiedades reológicas de emulsiones de sangre
Rheologic properties of blood emulsions

Se estudió la influencia de algunos factores sobre las propiedades reológicas de emulsiones grasas elaboradas con corpúsculos de sangre bovina. Las emulsiones que contienen sal, a los más altos niveles de adición de corpúsculos y caseinato, son las que presentan propiedades reológicas más cercana...