Results: 723

The effect of quercetin on cerulein-induced acute pancreatitis

OBJECTIVE: The aim of this study was to evaluate the protective and therapeutic effects of quercetin on pancreatic injury in cerulein-induced acute pancreatitis. METHOD: Thirty-two rats were randomly divided into four groups, eight per group: (CT): untreated controls, (CER) treated with cerulein, 50 µ...

Attenuation of partial unilateral ureteral obstruction - induced renal damage with hyperbaric oxygen therapy in a rat model

Int. braz. j. urol; 43 (5), 2017
ABSTRACT Objective: The objective of the present study was to evaluate the effectiveness of HBO therapy on biochemical parameters, renal morphology and renal scintigraphy in rats undergoing chronic unilateral partial ureteral obstruction (UPUO). Material and methods: Thirty-five rats were divided into ...

Modificaciones en el nivel de anión superóxido en leche materna, según la ingesta de flavonoides y carotenoides

Salud pública Méx; 59 (5), 2017
Resumen: Objetivo: Asociar la ingesta de flavonoides y carotenoides con el nivel en leche materna del anión superóxido, como marcador de estrés oxidativo. Material y métodos: Durante el periodo 2013-2015 se estudió a 100 mujeres lactantes de Córdoba (Argentina), dentro los primeros seis meses p...

Potential radioprotective effect of AT1 receptor antagonists against morphological and ultrastructural changes in the testes induced by ionizing radiation

Int. j. morphol; 35 (3), 2017
Radiotherapy is a source of human exposure to ionizing radiation. This pure energy causes deleterious effects on tissues, which result from oxidative stress, a phenomenon in which there is the participation of the Renin-Angiotensin System (RAS). The male genital organs are extremely radiosensitive and th...

Ethanol intake and toxicity: in search of new treatments

Int. j. morphol; 35 (3), 2017
Prolonged alcohol consumption has consequences on the liver, producing necrotic precipitates and fibrosis, on the pancreas, causing the pancreatic acini to atrophy and destroying insulin-producing cells, and on the central nervous system (CNS), causing the gray and white matter in the frontal lobes of th...

El análisis multivariado a partir del estado redox asociado a la preeclampsia
Multivariate Analysis from the Redox State Associated with Preeclampsia

Introducción: la preeclampsia es una enfermedad gestacional de origen placentario, de alta prevalencia, morbilidad y mortalidad materna y fetal. Numerosos estudios demuestran que el estrés oxidativo juega un rol significativo dentro de su fisiopatología activado por diferentes mecanismos implicados. O...

Putative 3-nitrotyrosine detoxifying genes identified in the yeast Debaryomyces hansenii: in silico search of regulatory sequences responsive to salt and nitrogen stress

Background: During salt stress, the yeast Debaryomyces hansenii synthesizes tyrosine as a strategy to avoid the oxidation of proteins. Tyrosine reacts with nitrogen radicals to form 3-nitrotyrosine. 3-nitrotyrosine prevents the effects of associated oxidative stress and thus contributes to the high halot...

Selenocysteine modulates resistance to environmental stress and confers anti-aging effects in C. elegans

Clinics; 72 (8), 2017
OBJECTIVE: The free radical theory of aging suggests that cellular oxidative damage caused by free radicals is a leading cause of aging. In the present study, we examined the effects of a well-known anti-oxidant amino acid derivative, selenocysteine, in response to environmental stress and aging using Ca...

Hyperin protects against cisplatin-induced liver injury in mice

Acta cir. bras; 32 (8), 2017
Abstract Purpose: To evaluate the effect of hyperin in cisplatin-induced liver injury in mice. Methods: Mice were pretreated with hyperin at doses of 25 mg/kg and 50 mg/kg, respectively, for six days, and intraperitoneal injection of cisplatin (40 mg/kg) was administrated one hour after the final intr...

Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats

Acta cir. bras; 32 (8), 2017
Abstract Purpose: To investigate the inflammatory and redox responses to teduglutide on an animal model of laparotomy and intestinal anastomosis. Methods: Wistar rats (n=62) were allocated into four groups: "Ileal Resection and Anastomosis" vs. "Laparotomy", each one split into "Postoperative Teduglut...