Alves, N T Q;
Ximenes, R M;
Jorge, R J B;
Silveira, J A M;
Santos, J V A;
Rodrigues, F A P;
Costa, P H S;
Xavier Jr, F A F;
Evangelista, J S A M;
Havt, A;
Soares, V C G;
Toyama, M H;
Oliveira, A N A;
Araújo, R M;
Alves, R S;
Monteiro, H S A.
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararac...
Antivenenos/aislamiento & purificación,
Antivenenos/farmacología,
Bothrops,
Venenos de Crotálidos/antagonistas & inhibidores,
Venenos de Crotálidos/toxicidad,
Modelos Animales de Enfermedad,
Relación Dosis-Respuesta a Droga,
Edema/tratamiento farmacológico,
Edema/etiología,
Hemorragia/tratamiento farmacológico,
Hemorragia/etiología,
Extractos Vegetales/farmacología,
Raíces de Plantas/química,
Polygalaceae/química
The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological potential against different ...
Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: Bth...
Abstract INTRODUCTION: We present here the risk from snakebites because of palm extractivism in western Amazonia. METHODS: The data were extracted from a cross-sectional sample study, from January 2016 to April 2018, at the Juruá Regional Hospital of Cruzeiro do Sul (Acre). RESULTS: There were 14 B...
Abstract INTRODUCTION: The popular names "surucucu" and "jararaca" have been used in literature for Lachesis muta and Bothrops atrox snakes, respectively. We present the popular names reported by patients who suffered snakebites in the Alto Juruá region. METHODS: Fifty-seven (76%) patients saw the s...
Resumo: No Brasil ocorrem anualmente cerca de 30.000 acidentes ofídicos, sendo os gêneros Bothrops e Crotalus responsáveis por 90% e 8% desses acidentes, respectivamente. Os envenenamentos botrópicos caracterizam-se por intensas reações inflamatórias locais, podendo evoluir para grandes perdas tec...
Snakebites are included in the group of emergencies for domestic animals, and these consultations demand technical knowledge as well as careful clinical evaluation of patients. Because of the importance of this theme and the higher prevalence of snakebites caused by snakes of the genus Bothrops in Rio Gr...
Roriz, Katia Regina Pena Schesquini;
Zaqueo, Kayena Delaix;
Setubal, Sulamita Silva;
Katsuragawa, Tony Hiroshi;
Silva, Renato Roriz da;
Fernandes, Carla Freire Celedônio;
Cardoso, Luiz Augusto Paiva;
Rodrigues, Moreno Magalhães de Souza;
Soares, Andreimar Martins;
Stábeli, Rodrigo Guerino;
Zuliani, Juliana Pavan.
Abstract INTRODUCTION Brazil has the largest number of snakebite cases in South America, of which the large majority is concentrated in the Midwest and North. METHODS In this descriptive observational study, we assessed the epidemiological and clinical snakebite cases referred to the Centro de Medici...
Antivenenos/administración & dosificación,
Bothrops,
Brasil/epidemiología,
Notificación de Enfermedades,
Elapidae,
Estudios Epidemiológicos,
Incidencia,
Persona de Mediana Edad,
Estaciones del Año,
Índice de Severidad de la Enfermedad,
Mordeduras de Serpientes/complicaciones,
Mordeduras de Serpientes/tratamiento farmacológico,
Mordeduras de Serpientes/epidemiología
A leucemia mieloide crônica (LMC) é uma neoplasia mieloproliferativa BCR-ABL1 + marcada por aumento da mieloproliferação e presença de células leucêmicas resistentes à apoptose. A terapia de primeira linha atual para a LMC é a administração de inibidores da tirosina quinase, mesilato de imatin...
L-amino acid oxidases isolated from snake venoms (SV-LAAOs) are enzymes that have great therapeutic potential and are currently being investigated as tools for developing new strategies to treat various diseases, including cancer and bacterial infections. The main objective of this study was to make a br...
