Resumen Introducción: si bien los cannabinoides se han utilizado durante varios años, apenas recientemente se han descrito los descubrimientos sobre sus mecanismos de acción y blancos terapéuticos, así como las alteraciones en el sistema endocannabinoide, observadas en diversas enfermedades y condi...
Resumen Los pacientes con colitis ulcerosa (CU) y enfermedad de Crohn (EC) presentan un mayor riesgo de cáncer colorrectal (CCR), debido a la inflamación crónica, la susceptibilidad genética y los factores de riesgo ambientales. Sin embargo, las neoplasias no epiteliales son infrecuentes. Presentamos...
ABSTRACT Objectives: To review the literature on oral and enteral nutrition therapy and investigate the evidence of its efficacy as a treatment, as well as in preventing relapses and reducing symptoms of inflammatory bowel diseases in the pediatric population. Data source: We performed a bibliographi...
ABSTRACT Background: Recently, with the performance of minimally invasive procedures for the management of colorectal disorders, it was allowed to extend the indication of laparoscopy in handling various early and late postoperative complications. Aim: To present the experience with laparoscopic reoper...
Resumen La enfermedad inflamatoria intestinal (EII) comprende un espectro de enfermedades crónicas inmunomediadas que afectan el tracto gastrointestinal, con inicio típico durante el comienzo de la edad adulta. Esta enfermedad ha tenido un incremento de su incidencia a nivel mundial, teniendo en Nortea...
Introdução: a colite ulcerativa é uma doença crônica que ocasiona inflamação das mucosas do cólon, ceco e reto. Algumas evidências sugerem que o desenvolvimento e as recidivas da colite estão relacionadas à susceptibilidade genética, ao desequilíbrio da microbiota
intestinal e à resposta an...
ABSTRACT BACKGROUND: The introduction of anti-TNF agents represented a landmark in the management of both Crohn's disease (CD) and ulcerative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facili...
Perin, Ramir Luan;
Damião, Aderson Omar Mourão Cintra;
Flores, Cristina;
Ludvig, Juliano Coelho;
Magro, Daniéla Oliveira;
Miranda, Eron Fábio;
Moraes, Antonio Carlos de;
Nones, Rodrigo Bremer;
Teixeira, Fábio Vieira;
Zeroncio, Marco;
Kotze, Paulo Gustavo.
ABSTRACT BACKGROUND: There is scarce data regarding efficacy and safety of vedolizumab in inflammatory bowel diseases in Latin America. OBJECTIVE: To describe the first observational real-world experience with vedolizumab in Latin American inflammatory bowel diseases patients. METHODS: Retrospectiv...
Ulcerative colitis is an idiopathic chronic inflammatory disease of the colon for which a lot of treatment modalities are present. However, significant side effects are associated with them, and there is a need for a search for other tretment options. This study was aimed to assess the contribution of ni...