Resumen Introducción: La cirugía de cardiopatías congénitas puede generar alteraciones perfusorias cerebrales con repercusión neurológica. Objetivo: Analizar la relación del índice de resistencia (IR) vascular cerebral periquirúrgico con funciones neurológicas mediatas posteriores a cirugía ...
Abstract Reinforced endotracheal tubes (ETTs) are regularly applied in anesthetic practices to prevent compression or kinking. Although these tubes are designed to bend easily and prevent obstruction, they still carry a potential hazard of being obstructed following external forces. In this article, we r...
Patent foramen ovale (PFO) is a prevalent congenital septal atrial defect usually without pathological significance. In certain pathogenic situations, PFO can trigger episodes of recurrent hypoxemia, a specific condition known as platipnea-orthodeoxia syndrome (POS). We report a 73 years old female prese...
OBJECTIVES: Hypoxia leads to endothelial cell inflammation, apoptosis, and damage, which plays an important role in the complications associated with ischemic cardiovascular disease. As an oxidoreductase, p66Shc plays an important role in the regulation of reactive oxygen species (ROS) production and apo...
Introdução: O uso do laser infravermelho (LIV) através da fotobiomodulação, tem demonstrado efeitos benéficos aos tecidos. Objetivos: Avaliar a influência do LIV sobre o processo inflamatório, por meio da imunomarcação da interleucina próinflamatória IL-23, e sobre a angiogênese, por meio da...
Blanqueamiento de Dientes,
Heridas Penetrantes,
Hipoxia,
Inflamación,
Interleucina-23,
Interleucinas,
Pulpa Dental,
Ratas Wistar,
Terapia por Láser,
Terapia por Luz de Baja Intensidad,
Inflamación/terapia
Abstract Purpose To evaluate the effect of N-Acetylcysteine (NAC) in newborn rats submitted to hypoxia and reoxygenation (H/R) conditions in an experimental model of necrotizing enterocolitis. Methods Eight pregnant rats and their 70 cubs were used (5 groups) and exposed to H/R conditions and receive...
Acetilcisteína/farmacología,
Modelos Animales de Enfermedad,
Enterocolitis Necrotizante/prevención & control,
Hipoxia/patología,
Íleon/efectos de los fármacos,
Íleon/patología,
Sustancias Protectoras/farmacología,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
BACKGROUND: Hypoxia inducible factor-1 (HIF-1) is considered as the most activated transcriptional factor in response to low oxygen level or hypoxia. HIF-1 binds the hypoxia response element (HRE) sequence in the promoter of different genes, mainly through the bHLH domain and activates the transcription ...
Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/metabolismo,
Hipoxia/metabolismo,
Factor 1 Inducible por Hipoxia/metabolismo,
Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética,
Western Blotting,
Expresión Génica,
Células HEK293,
Hipoxia/genética,
Factor 1 Inducible por Hipoxia/genética,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Activación Transcripcional/genética
RESUMO Objetivo Verificar a associação entre massa e espessura do ventrículo esquerdo (VE) e presença de hipoxemia noturna significativa em pacientes portadores de DPOC com hipoxemia diurna leve. Métodos Estudo transversal realizado em pacientes ambulatoriais, clinicamente estáveis, portadores de...
Estudios Transversales,
Ecocardiografía/métodos,
Ventrículos Cardíacos/anatomía & histología,
Ventrículos Cardíacos/diagnóstico por imagen,
Hipertrofia Ventricular Izquierda/etiología,
Hipoxia/etiología,
Hipoxia/fisiopatología,
Polisomnografía/efectos adversos,
Enfermedad Pulmonar Obstructiva Crónica/complicaciones,
Enfermedad Pulmonar Obstructiva Crónica/fisiopatología,
Síndromes de la Apnea del Sueño/fisiopatología,
Espirometría
Ischemic heart disease (IHD) is one of the leading causes of death worldwide. C-type lectin domain family 3 member B (CLEC3B) is a C-type lectin superfamily member and is reported to promote tissue remodeling. The serum levels of CLEC3B are downregulated in patients with cardiovascular disease. However, ...
Multicystic encephalomalacia is varying sized cystic lesions in the brain encountered in developing fetuses or infants. These cysts start at the periventricular area and may extend onto the cortex. The cause of the formation of these cystic lesions is secondary to an ischemic or hypoxic insult, which lea...
