Background: Pseudomonas aeruginosa is a common opportunistic pathogenic bacterium with the ability to develop a strong communication pathway by quorum sensing system and different virulent factors. Among the various important secretions of P. aeruginosa rhamnolipid is important biological detergent, beli...
ABSTRACT Leprosy can be considered a dissimulated disease, mainly when presented as atypical cases leading to mistaken diagnosis at the emergency setting. Herein we report six patients referred to the emergence room with hypotheses of acute myocardial infarction and arterial and venous thrombosis, althou...
RESUMO Objetivo: Investigar os fatores de risco associados ao adoecimento por hanseníase em contatos de casos da doença. Métodos: Realizou-se uma revisão sistemática e metanálise com busca nas bases de dados: Medical Literature Analysis and Retrieval System Online (MEDLINE), Embase, Cochrane ...
Abstract Sophorolipids are glycolipids that have natural antimicrobial properties and present great potential in the pharmaceutical field. The present study aimed to produce sophorolipids from Candida bombicola using a chicken fat-based medium and evaluate the antimicrobial activity against Gram-negative...
Resumo Relata-se um caso de uma paciente com doença de Guacher tipo III, com mutação no Exon9, 1246G>A e 1251G>C, buscando investigar a suspeita de glaucoma, descrever os achados oftalmológicos, como acumulo de glicolipideo em região pré- retiniana e investigar a possível correlação com a ...
Enfermedad de Gaucher/complicaciones,
Enfermedad de Gaucher/genética,
Agudeza Visual,
Oftalmopatías/diagnóstico por imagen,
Oftalmopatías/etiología,
Retina/diagnóstico por imagen,
Tomografía de Coherencia Óptica,
Glucolípidos/metabolismo,
Glaucoma/diagnóstico,
Nervio Óptico/diagnóstico por imagen,
Fibras Nerviosas
Abstract Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, wh...
Anticuerpos Antibacterianos/administración & dosificación,
Antígenos Bacterianos/análisis,
Antígenos Bacterianos/inmunología,
Trazado de Contacto,
Ensayo de Inmunoadsorción Enzimática,
Familia,
Glucolípidos/análisis,
Glucolípidos/inmunología,
Lepra Multibacilar/diagnóstico,
Lepra Paucibacilar/diagnóstico,
Mycobacterium leprae/inmunología,
Saliva/química,
Saliva/inmunología
BACKGROUND There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disacchari...
Abstract: An integrative literature review was conducted to synthesize available publications regarding the potential use of serological tests in leprosy programs. We searched the databases Literatura Latino-Americana e do Caribe em Ciências da Saúde, Índice Bibliográfico Espanhol em Ciências da Sa�...
Abstract: INTRODUCTION: Leprosy is mainly transmitted among family members who share genetic and ambient factors. The clinical form of leprosy in the index case and kinship could be risk factors for leprosy transmission. High antibody levels in household contacts (HC) in the absence of neural or skin les...
Anticuerpos Antibacterianos/sangre,
Antígenos Bacterianos/sangre,
Trazado de Contacto,
Ensayo de Inmunoadsorción Enzimática,
Composición Familiar,
Glucolípidos/sangre,
Inmunoglobulina M/sangre,
Lepra/diagnóstico,
Lepra/transmisión,
Persona de Mediana Edad,
Factores de Riesgo
Nesta tese, foi demonstrado que o anticorpo monoclonal (MoAb) MEST-1, o qual reconhece resíduos terminais de galactofuranose ligados b1-3 ou b1-6 à manose, apresentou alta reatividade com formas promastigotas de L. (L.) major, sendo que o antígeno reconhecido neste parasita é o GIPL-1. Por imunoeletr...
