Epilepsy is the chronic non-communicable disease of the nervous system most prevalent in the world. Valproic acid (VPA) is one of the most used drugs in the treatment of epilepsy but with various side effects. One of the organs that can be affected is the testis, where it has been seen that men treated w...
El ácido valproico (VPA) es un fármaco antiepiléptico teratógenico que, al ser administrado durante etapas tempranas del embarazo, puede producir alteraciones en el desarrollo embriofetal, las que se manifiestan tanto a nivel del sistema nervioso como del testículo. No obstante, se ha reportado que ...
O Neuroblastoma (NB) é uma neoplasia do sistema nervoso simpático, e o segundo tumor sólido maligno extracraniano mais comum da infância. Na terapia antineoplásica, complicações orais podem ser observadas, dentre elas a mucosite oral (MO). Trata-se de uma inflamação aguda da mucosa, proveniente ...
Abstract The incorporation of antioxidants into sunscreens may provide additional skin photoprotection against the harmful photobiological effects of ultraviolet radiation. The present study evaluated the applicability of a screening approach to the assessment of the antioxidant and photoprotective prope...
Introdução: As doenças cardiovasculares (DCV) são a principal causa de morbimortalidade
no mundo. Diante disso, são estudadas estratégias de prevenção e tratamento de eventos
cardiovasculares. Dentre elas, a vitamina E destaca-se por suas propriedades antioxidantes e
anti-inflamatórias, apoiado ...
Estado Nutricional,
Vitamina E/uso terapéutico,
Factores de Riesgo de Enfermedad Cardiaca,
Indicadores de Morbimortalidad,
Estudios Transversales/métodos,
Estudios Poblacionales en Salud Pública,
alfa-Tocoferol/uso terapéutico,
Deficiencia de Vitamina E/patología,
Modelos Lineales,
Brasil/epidemiología,
Ingestión de Alimentos
SUMMARY: An association between certain food additives and chronic diseases is reported. Current study determined whether administering toxic doses of the food additive monosodium glutamate (MSG) into rats can induce aortopathy in association with the oxidative stress and inflammatory biomarkers upregula...
Aorta/efectos de los fármacos,
Vitamina E/farmacología,
Glutamato de Sodio/toxicidad,
Enfermedades de la Aorta/inducido químicamente,
Estrés Oxidativo/efectos de los fármacos,
Modelos Animales de Enfermedad,
Microscopía Electrónica,
Aorta/patología,
Vitamina E/administración & dosificación,
Glutamato de Sodio/administración & dosificación,
Ratas Sprague-Dawley,
Malondialdehído/antagonistas & inhibidores,
Interleucina-6/antagonistas & inhibidores,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores
SUMMARY: In testicular differentiation, somatic cells must adopt a specific destiny towards sustentacular, peritubular and interstitial cells, being fundamental for the morphogenesis of seminiferous tubules, mediated by morphogens such as Desert Hedgehog (DHH), insulin-like growth factor-1 (IGF-1) and fi...
Canine sperm is a very delicate cell that is quite susceptible to oxidative stress since the cytoplasm is restricted and features little antioxidant reserves. Furthermore, the sperm membrane has some polyunsaturated fatty acids sensitive to lipid peroxidation, which makes it important to addition antioxi...
ABSTRACT Objective: To assess vitamin E intake and its relationship with sociodemographic variables, and to identify the main dietary sources of the nutrient in the diet of adolescents. Methods: This is a population-based cross-sectional study that used data from 891 adolescents living in Campinas, S...
Antioxidantes/administración & dosificación,
Antioxidantes/análisis,
Brasil,
Estudios Transversales,
Dieta Occidental/efectos adversos,
Grasas de la Dieta/administración & dosificación,
Conducta Alimentaria,
Encuestas Nutricionales,
Necesidades Nutricionales,
Estado Nutricional,
Vitamina E/administración & dosificación,
Vitamina E/análisis
In the present study, the effect of vitamin E supplementation 450 mg/kg diet was appraised in the process of induced wound healing in Nile tilapias Oreochromis niloticus. Fish were distributed into 18 tanks (10 fish each). Nine tanks were fed the non-supplemented diet and the other 9 tanks were fed 450 m...
