HIV/AIDS is a leading cause of infant mortality in sub-Saharan Africa. Despite significant improvements in preventing vertical transmission, in the 21 Global Plan priority countries in sub-Saharan Africa, over 100 000 infants are infected with HIV annually and only 50% access life-saving antiretroviral t...
Mozambique is a sub-Saharan African country with limited information on the burden
of fungal disease. We estimated the burden of serious fungal infections for the general healthy
population and for those at risk, including those infected with HIV, patients with asthma, as well as
those under intensive...
Retention in anti-retroviral therapy (ART) presents a challenge in sub-Saharan Africa. In
Mozambique, after roll-out to peripheral facilities, the 12-month retention rate was reported
mostly from sites with an electronic patient tracking system (EPTS), representing only 65%
of patients. We conducted a na...
Anti-HIV Agents/pharmacology,
CD4 Lymphocyte Count,
Death,
Lost to Follow-Up,
Patient Identification Systems,
HIV,
Adolescent,
Mozambique/epidemiology,
HIV Testing,
Anti-Retroviral Agents/therapeutic use,
HIV/drug effects,
Pregnancy
Megg, Bindiya;
Vojnov, Lara;
Mabunda, Nédio;
Vubil, Adolfo;
Zitha, Alcina;
Tobaiwa, Ocean;
Mudenyanga, Chishamiso;
Mutsaka, Dadirayi;
Bollinger, Timothy;
Loquiha, Osvaldo;
Pete, Trevor F;
Jan, Ilesh V.
Worldwide only 43% of infants infected with HIV have access to antiretroviral treatment (ART). Despite significant global efforts to expand access to paediatric treatment, coverage lags behind adult ART and may not reach the 90-90-90 goals by 2020 as set by UNAIDS [2]. Resolving this paediatric ART gap i...
Viegas, Edna O;
Kroidl, Arne;
Munser, Patricia J;
Missanga, Marco;
Nilsson, Charlotta;
Tembe, Nelson;
Bauer, Asli;
Joachim, Agricola;
Joseph, Sarah;
Mann, Philipp;
Geldmache, Christof;
Fleck, Sue;
Stohr, Wolfgang;
Scarlatti, Gabriella.
Although there has been a decline in the number of new human immunodeficiency virus (HIV) infections over the years, millions of people continue to be exposed and infected [1]. More than 200 HIV vaccine phase I and II, and 6 efficacy trials have been conducted [2, 3]. The RV144 Thai trial is the only tri...
AIDS Vaccines/immunology,
HIV Infections/prevention & control,
Immunogenicity, Vaccine,
Immunization, Secondary/methods,
Mozambique/epidemiology,
Tanzania,
Vaccines, DNA/genetics,
env Gene Products, Human Immunodeficiency Virus/genetics
Fuente-Soro, Laura;
Lopez-Varela, Elisa;
Augusto, Orvalho;
Sacoor, Charfudin;
Nhacolo, Ariel;
Nhacolo, Ariel;
Honwana, Nely;
Karajeanes, Esmeralda;
Vaz, Paula;
Naniche, Denise.
This analysis was nested in a prospective cohort established in southern Mozambique which conducted three HIV-testing modalities: voluntary counselling and testing (VCT), provider-initiated counselling and testing (PICT) and home-based testing (HBT). Participants were given the opportunity to self-report...
Sacarlal, Jahit;
Muchanga, Vasco;
Mabutana, Carlos;
Mabui, Matilde;
Cuamba, Assa Júlio;
Mariamo, Arlete;
Fumo, Leida Artur;
Silveira, Jacinta;
Heitman, Elizabeth;
Moon, Troy D.
Mozambique has seen remarkable growth in biomedical research over the last decade. To meet a
growing need, the National Committee for Bioethics in Health of Mozambique (CNBS) encouraged the development of
ethical review processes at institutions that regularly conduct medical and social science research....
Bioethics,
Ethical Analysis,
Ethics Committees, Research,
Hospitals, University,
Universities,
Ethics, Medical/education,
Mozambique/epidemiology,
Biomedical Research,
Ethical Review
Background: Malaria continues to be a major public health concern in Africa. Approximately 3.2 billion people worldwide are still at risk of contracting malaria, and 80% of deaths caused by malaria are concentrated in only 15 countries, most of which are in Africa. These high-burden countries have achiev...
Climate,
Malaria/epidemiology,
Socioeconomic Factors,
Spatial Analysis,
Altitude,
Geographic Information Systems,
Geographic Mapping,
Mozambique/epidemiology,
Prevalence,
Public Health,
Risk Assessment,
Risk Factors,
Temperature
Background: On 9 January 2015, in a rural town in Mozambique, >230 persons became sick and 75 died of an illness linked to drinking pombe, a traditional alcoholic beverage.
Methods: An investigation was conducted to identify case patients and determine the cause of the outbreak. A case patient was define...
Gudo, Eduardo Samo;
Cook, Kyla;
Kasper, Amelia M;
Vergara, Alfredo;
Salomão, Cristolde;
Oliveira, Fernanda;
Ismael, Hamida;
Saeze, Cristovão;
Mosse, Carla;
Fernandes, Quinhas;
Viegas, Sofia Omar;
Baltazar, Cynthia Semá;
Doyle, Timothy J;
Yard, Ellen;
Steck, Alaina;
Serret, Mayda;
Falconer, Travis M;
Kern, Sara E;
Brzezinski, Jennifer L;
Turner, James A;
Boyd, Brian L;
Jani, Ilesh V.
Background: On 9 January 2015, in a rural town in Mozambique, >230 persons became sick and 75 died of an illness linked to drinking pombe, a traditional alcoholic beverage.
Methods: An investigation was conducted to identify case patients and determine the cause of the outbreak. A case patient was define...
