Hepatitis B virus (HBV) infects nearly 300 million people and is the leading cause of hepatitis and hepatocellular carcinoma worldwide. Despite the high burden of HBV in sub-Saharan Africa, countries such as Mozambique have limited data available on circulating HBV genotypes and the presence of drug resi...
Strydom, Amy;
Donato, celeste m;
Nyaga, martin m;
Boene, simone s;
Peenze, Ina;
Mogotsi, Milton T;
João, Eva D;
Munlela, benilde;
Potgieter, A. Christiaan;
Seheri, mapaseka L;
de Deus, Nilsa;
O’Neill, hester G.
This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without prior adaptation to cell culture, was used to synthesise cDNA using a self-annealing anchor primer ligated to dsRNA and random hexamers. The cDNA...
Boane, Simone S;
João, Eva D;
Strydom, Amy;
Munlela, Benilde;
Chissaque, Assucênio;
Bauhofer, Adilson Fernando Loforte;
Nabetse, Elvino;
Dalilo, Latifo;
Cala, Aida;
Mapaco, Lourenço;
Chilaúle, Jorfélia;
O'Neill, Hester G;
Deus, nilza.
Rotavirus A (RVA) is an important pathogen causing gastroenteritis in many species, including humans and pigs. The objective of this study was to determine the prevalence of RVA in pigs from smallholdings and commercial farms in southern Mozambique and characterize the complete genomes of selected strain...
Ongaro, Linda;
Ludovica, Molinaro;
Flores, Rodrigo;
Marnetto, Davide;
Capodiferro, Marco R;
Riquelme, Marta E. Alarcón;
Estrada, Andrés Moreno;
Mabunda, Nedio;
Ventura, Mario;
Tambets, Kristiina;
Achilli, Alessandro;
Capelli, Cristian;
Metspalu, Mait;
Pagani, Luca;
Montinaro, Francesco.
A general imbalance in the proportion of disembarked males and females in the Americas has been documented during the Trans-Atlantic Slave Trade and the Colonial Era and, although less prominent, more recently. This imbalance may have left a signature on the genomes of modern-day populations characterise...
A doença diarreica na infância constitui um importante problema de saúde
pública em Moçambique. A infecção pelo Rotavirus é a uma das causas mais comum de diarreia
aguda grave a nível mundial, sendo a diarreia terceira causa de morbi-mortalidade infantil na
maioria d...
Joao, eva dora;
Stroydon, amey;
Oneil g, hester;
Cumba, assa;
Cossecera, marta;
Acacio, sozinho;
Mandomando, inácio;
Motanyane, lithabiso;
Page, nicola;
Deus, nilsa de.
In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, c...
Gastroenterite/virologia,
Genótipo,
Infecções por Rotavirus/virologia,
Doença Aguda,
Filogenia,
Rotavirus/genética,
Antígenos Virais/genética,
Variação Genética,
Regulação Viral da Expressão Gênica,
Moçambique,
Epitopos/genética
Jordan, M Michael;
Penazzato, Martina;
Cournil, Amandine;
Vubil, Adolfo;
Jani, Ilesh;
Hunt, Gilian;
Maphalala, Gudo;
Carmona, Sergio;
Mthethwa, Nobuhle;
Watera, Christine;
Kaleebu, Pontiano;
Musanhu, Christine Chaknyuka;
Mtapuri-Zinyowera, Sekasai;
Dzangare, Janet;
Peeters, Martine;
Yang, Chunfu;
Parkin, Iveil;
Bertagnolio, Silvia.
Background. Programs for the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) have been scaled up in many low- and middle-income countries. However, HIV drug resistance (HIVDR) data among HIV-1– infected young children remain limited.
Methods. Surveys of pretreat...
Acute diarrhea disease caused by Rotaviruses A (RVA) is still the leading cause of morbidity and mortality in children ≤5 years old in developing countries. An exploratory cross-sectional study was conducted between February and September, 2011 to determine the proportion of acute diarrhea caused by RV...
A tuberculose (TB) é uma doença infecciosa que ameaça a humanidade há séculos. Recentemente grandes
avanços foram conseguidos no combate à tuberculose, entretanto a resistência bacilar e a coinfecção pelo
Vírus de Imunodeficiência Humana (HIV) persistem como os principais desafios dos program...
Farmacorresistência Bacteriana,
Mycobacterium tuberculosis/efeitos dos fármacos,
Genótipo,
Antibióticos Antituberculose/farmacologia,
Coinfecção,
Tuberculose Resistente a Múltiplos Medicamentos/microbiologia,
Prevalência,
Tuberculose/microbiologia,
Testes de Sensibilidade Microbiana,
Mycobacterium tuberculosis/genética,
Infecções por HIV/epidemiologia,
Moçambique/epidemiologia
Smith, Anthony M;
Lafourcade, Berthe-Marie Njanpop;
Mengel, Martin A;
Gessner, Bradford D;
Sauvageot, Delphine;
Bidjada, Bawimodom;
Miwanda, Berthe N;
Saliou, Diallo M;
N'Douba, Adèle Kacou;
Langa, José P;
Ismail, Husna;
Tau, Nomsa;
Sooka, Arvinda;
Keddy, Karen H.
We used standardized methodologies to characterize Vibrio cholerae O1 isolates from Guinea, Democratic Republic of the Congo (DRC), Togo, Côte d’Ivoire and Mozambique. We investigated 257 human isolates collected in 2010 to 2013. DRC isolates serotyped O1 Inaba, while isolates from other countries ser...
África Subsaariana/epidemiologia,
Cólera/epidemiologia,
Genótipo,
Fenótipo,
Filogenia,
Vigilância da População,
Vibrio cholerae O1/classificação,
Cólera/microbiologia,
Resistência a Múltiplos Medicamentos,
Ciprofloxacina,
Ceftriaxona,
Vibrio cholerae O1/genética
