Background: An observational study was conducted in Maputo, Mozambique, to investigate trends in prevalence of HIV drug resistance (HIVDR) in antiretroviral (ART) naïve subjects initiating highly active antiretroviral treatment (HAART).
Methodology/principal findings: To evaluate the pattern of drug res...
O HIV é um retrovírus de evolução rápida caracterizado por uma enorme diversidade genética. Os eventos de recombinação durante a transcrição reversa, a elevada taxa de replicação viral e a incapacidade da transcriptase reversa em corrigir erros de incorporação de nucleotídeos nas cadeias e...
Background Anobservational study was conducted in Maputo, Mozambique, to investigate trends in prevalence of HIV drug resistance (HIVDR) in antiretroviral (ART) naïve subjects initiating highly active antiretroviral treatment (HAART).
Methodology/Principal Findings
Toevaluate the pattern of drug resis...
Background HIV/ HBVcoinfected patients are at high risk of developing chronic HBV infection, liver cir rhosis and hepatocellular carcinoma. In Mozambique, where HIV prevalence is one of the highest in the world, HIV-infected patients are scarcely characterized in terms of HBV coin fection and 3TC-resista...
HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good results in mon...
Long-lasting insecticide-treated nets (LLINs) are one of the main methods used for controlling malaria
transmission in Mozambique. The proliferation of several types of LLINs and the re-emergence of insecticide resistance in the local vector populations poses challenges to the local malaria control prog...
