Medullary thyroid carcinoma (MTC) may rarely present with paraneoplastic syndromes. Among the most frequent ones are the appearance of diarrhea and ectopic Cushing syndrome (ECS). The ECS in the context of MTC is usually present in patients with distant metastatic disease. The use of drugs such as ketoco...
Carcinoma Neuroendocrino/complicaciones,
Carcinoma Neuroendocrino/tratamiento farmacológico,
Síndrome de Cushing/tratamiento farmacológico,
Síndrome de Cushing/etiología,
Progresión de la Enfermedad,
Estadificación de Neoplasias,
Piperidinas/uso terapéutico,
Quinazolinas/uso terapéutico,
Neoplasias de la Tiroides/complicaciones,
Neoplasias de la Tiroides/tratamiento farmacológico,
Resultado del Tratamiento
Advanced radioactive refractory and progressive or symptomatic differentiated thyroid carcinoma (DTC) is a rare condition. Sorafenib was recently approved for the treatment of these patients. We present the case of a 67 year old woman diagnosed with DTC who underwent a total thyroidectomy with central, l...
Antineoplásicos/administración & dosificación,
Antineoplásicos/uso terapéutico,
Recurrencia Local de Neoplasia/terapia,
Estadificación de Neoplasias,
Niacinamida/administración & dosificación,
Niacinamida/análogos & derivados,
Niacinamida/uso terapéutico,
Compuestos de Fenilurea/administración & dosificación,
Compuestos de Fenilurea/uso terapéutico,
Tomografía Computarizada por Tomografía de Emisión de Positrones,
Sorafenib,
Trombocitopenia/inducido químicamente,
Neoplasias de la Tiroides/complicaciones,
Neoplasias de la Tiroides/terapia,
Tiroidectomía
INTRODUCTION: Elective neck dissection is recommended in cases of oral cavity squamous cell carcinoma without lymph node metastasis because of the risk of occult metastasis. OBJECTIVE: The present study aimed to evaluate predictive factors for occult lymph node metastasis in patients with oral cavity squ...
Carcinoma de Células Escamosas/cirugía,
Procedimientos Quirúrgicos Electivos,
Ganglios Linfáticos/patología,
Neoplasias de la Boca/cirugía,
Disección del Cuello/métodos,
Carcinoma de Células Escamosas/mortalidad,
Carcinoma de Células Escamosas/patología,
Métodos Epidemiológicos,
Metástasis Linfática/diagnóstico,
Metástasis Linfática/patología,
Neoplasias de la Boca/mortalidad,
Neoplasias de la Boca/patología,
Estadificación de Neoplasias,
Tasa de Supervivencia
Introduction: An accurate preoperative rectal cancer staging is crucial to the correct management of the disease. Despite great controversy around this issue, pelvic magnetic resonance (RM) is said to be the imagiologic standard modality. This work aimed to evaluate magnetic resonance accuracy in preoper...
INTRODUCTION: Occurrence of apoptosis and expression of proliferative markers are powerful tools to establish a prognosis in the follow-up of cancer. OBJECTIVE: To evaluate the growth fraction in papillomas and laryngeal squamous cell carcinomas with three degrees of differentiation through apoptosis and...
Apoptosis,
Carcinoma de Células Escamosas/patología,
Neoplasias de Cabeza y Cuello/patología,
Neoplasias Laríngeas/patología,
Región Organizadora del Nucléolo/patología,
Neoplasias Glandulares y Epiteliales/patología,
Papiloma/patología,
Biomarcadores de Tumor,
Estudios Transversales,
Estadificación de Neoplasias,
Pronóstico
Introdução: O câncer bucal representa um grave problema de saúde pública no Brasil e no mundo. As informações dos casos diagnosticados por câncer, assim como os indicadores de mortalidade por essa doença, traduzem o perfil da população acometida por ela, além de auxiliar na formulação de po...
O tumor de células gigantes (TCG) do osso é uma lesão benigna, localmente agressiva, que compromete as extremidades dos ossos longos principalmente da articulação do joelho e o rádio distal. É um tumor que tem comportamento biológico imprevisível que não guarda relação com as características...
OBJECTIVE To estimate the budget impact from the incorporation of positron emission tomography (PET) in mediastinal and distant staging of non-small cell lung cancer.METHODS The estimates were calculated by the epidemiological method for years 2014 to 2018. Nation-wide data were used about the incidence;...
Carcinoma de Pulmón de Células no Pequeñas/diagnóstico por imagen,
Carcinoma de Pulmón de Células no Pequeñas/economía,
Carcinoma de Pulmón de Células no Pequeñas/patología,
Neoplasias Pulmonares/diagnóstico por imagen,
Neoplasias Pulmonares/economía,
Neoplasias Pulmonares/patología,
Persona de Mediana Edad,
Estadificación de Neoplasias/economía,
Estadificación de Neoplasias/métodos,
Tomografía de Emisión de Positrones/economía,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad
BACKGROUND: Transforming growth factor (TGF)-β is involved in many physiologic processes, it often promotes metastasis, and its high expression is correlated with poor prognosis. In the present study, we analyzed the correlation between transforming growth factor beta 1 (TGF-β1) expression and prognosi...
Colangiocarcinoma/metabolismo,
Neoplasias Hepáticas/metabolismo,
Proteínas de Neoplasias/metabolismo,
Factor de Crecimiento Transformador beta1/metabolismo,
Biomarcadores de Tumor/sangre,
Colangiocarcinoma/mortalidad,
Colangiocarcinoma/patología,
Colangiocarcinoma/secundario,
Neoplasias Hepáticas/mortalidad,
Neoplasias Hepáticas/patología,
Inmunohistoquímica,
Estimación de Kaplan-Meier,
Metástasis Linfática,
Estadificación de Neoplasias,
Factores de Tiempo
Introduction: Carcinoid tumors are neuroendocrine malignancies that originate in the neuroectodermal cells of the Amine, Peptide Uptake and Decarboxylation system dispersed in the gastrointestinal mucosa and representing about 80-88% of tumors of cecal appendix. These are tumors usually diagnosed at appe...
